Past CCTS Courses

2016-2017

Summer 2017

CCTS 45200/PPHA 47900/PBHS 35000
Fundamentals of Health Services Research
Instructors: David Meltzer, MD, PhD, and Marshall Chin, MD, MPH; others TBA
Time: Mondays/Tuesdays/Wednesdays/Thursdays/Fridays, 1:00-2:30 PM
Location: Billings Hospital, H300
This course is designed to provide an introduction to the fundamentals of health services research. The basic concepts of health services research will be taught with emphasis on both their social scientific foundations and the methods needed for their practical application to empirically relevant research. Theoretical foundations will draw on principles from economics, sociology, psychology, and the other social sciences. Methodological topics to be covered will include techniques for data collection and analysis, including outcomes measurement, survey methods, large data set research, population-based study design, community based participatory research, research based in clinical settings, qualitative methods, cost-effectiveness analysis, and tools of economic and sociological analysis. The theoretical and empirical techniques taught will emphasize those relevant to the examination of health care costs, quality, and access. Major applications will include: measurement and improvement of health care quality, analysis of health disparities, analysis of health care technology, and analysis of health care systems and markets. Students prepare a grant proposal as the final assignment for this course. 

PBHS 32100/CCTS 45000
Introduction to Biostatistics

Instructors: John Cursio, PhD
Time: 3:00-4:30 PM, Tuesdays, Wednesdays, and Thursdays
Location: TBA
This course will provide an introduction to the basic concepts of statistics as applied to the bio-medical and public health sciences. Emphasis is on the use of interpretation of statistical tools for data analysis. Topics include (i) descriptive statistics; (ii) probability and sampling; (iii) the methods of statistical inference; and (iv) an introduction to linear and logistics regression.

PBHS 30700/CCTS 45100
Clinical Epidemiology

Instructors: Diane Lauderdale, PhD, and Brian Chiu, PhD
Time: 9:00-11:00 am, Tuesdays and Thursdays
Location: TBA
Clinical epidemiology is the “application of epidemiologic principles and methods to problems encountered in clinical medicine.” This course introduces the basic principles of epidemiologic study design, analysis and interpretation, with a particular focus on clinical applications. The course includes lectures and discussions based on critical appraisal of significant research articles.

Spring 2017 Courses

CCTS 21003
Topics in Clinical Research

Instructor: Valerie Press
Time: Mondays and Wednesdays, 1:30-2:50 pm
Location: Billings P315
This course provides an overview of clinical research subject matter from the history and ethics of clinical research to the types and practice of contemporary clinical research. How does clinical research differ from other research traditions? What is special about clinical research? What types of questions can be answered by clinical research (what questions not)? What types of ethical oversight over the responsible conduct of research have arisen over the years? We will learn how to read and critique clinical research, survey the major types of clinical research designs, and the differences between hypothesis generation and hypothesis testing. Finally, we provide an overview of the mechanics of developing and implementing clinical research, including grant writing, regulatory issues, and quality assurance. Along the way, we will be teaching core statistical concepts including prevalence, risk ratios, and sensitivity and validation techniques. The objectives are for students to obtain an understanding of how and why to perform clinical research and to do so in an ethical and responsible manner.

CCTS 38300
Health Economics and Public Policy

Instructor:  David Meltzer
Time: Tuesdays and Thursdays, 1:30-2:50 pm
Location: TBD
This course analyzes the economics of health and medical care in the United States with particular attention to the role of government. The first part of the course examines the demand for health and medical and the structure and the consequences of public and private insurance. The second part of the course examines the supply of medical care, including professional training, specialization and compensation, hospital competition, and finance and the determinants and consequences of technological change in medicine. The course concludes with an examination of recent proposals and initiatives for health care reform.

CCTS 40006
Pharmacogenomics: Discovery and Implementation
Instructor: Barbara Stranger, R. Stephanie Huang
Time: Mondays and Wednesdays, 10:30-11:50 am
Location: BSLC 305
Pharmacogenomics is aimed at advancing our knowledge of the genetic basis for variable drug response. Advances in genetic knowledge gained through sequencing have been applied to drug response, and identifying heritable genetic variants that predict response and toxicity is an area of great interest to researchers. The ultimate goal is to identify clinically significant variations to predict the right choice and dose of medications for individuals—"personalizing medicine." The study of pharmacogenomics is complicated by the fact that response and toxicity are multigenic traits and are often confounded by nongenetic factors (e.g., age, co-morbidities, drug-drug interactions, environment, diet). Using knowledge of an individual's DNA sequence as an integral determinant of drug therapy has not yet become standard clinical practice; however, several genetics-guided recommendations for physicians have been developed and are highlighted. The ethics and economics of pharmacogenomics are also discussed.

Undergrads (3rd & 4th years only) must have taken BIOS 20187 and are required to email instructors for approval (bstranger@medicine.bsd.uchicago.edu & rhuang@medicine.bsd.uchicago.edu) prior to registering. Meets requirement for Bio Majors as part of Cancer Specialization.

CCTS 43200
Infectious Disease Epidemiology; Networks and Modeling

Instructor: Michael David
Time: Mondays and Wednesdays, 3:00-4:20pm
Location: TBD
This intermediate-level epidemiology course directed by two infectious disease epidemiologist-physicians will provide an up to date perspective on forgotten, contemporary and emerging infections. The course lectures and readings will provide a rigorous examination of the interactions among pathogens, hosts and the environment that produce disease in diverse populations. In addition to the demographic characteristics and the behaviors of individuals that are associated with a high risk of infection, we will examine complex aspects of the environment as they pertain to disease transmission. These include poverty, globalization, social networks, public health, and racial and ethnic disparities. Methodologic approaches to infectious disease epidemiology that will be covered include traditional study designs, molecular epidemiology, social network analysis, modeling, and network science. Local and global approaches will be applied to case studies from the United States, Asia and Africa.

PBHS 30700 or PBHS 30900 or introductory epidemiology or consent of instructor. For Biology majors: Completion of three quarters of a Biological Sciences Fundamentals Sequence.

CCTS 47007
Methods in Health and Biomedical Informatics III

Instructors: David McClintock and Samuel Volchenboum
Time: Thursdays, 1:30-3:30 pm, From January 12 until March 9
Location: Varies between Northwestern downtown campus, UIC, and UC
Most Health and Biomedical Informatics (HBMI) Graduate Programs around the country have independently come to the conclusion that the computational methods that informatics graduate students need to be familiar with is too broad and numerous to be addressed by a series of independent courses. Therefore, most programs have created a set of integrated courses that expose the students to a wide variety of informatics methods in short modules. Typically, these required methods series are organized as a series of required courses taken during the first year of graduate study. This course is the result of discussions by Health and Biomedical Informatics researchers and educators from the Chicago Biomedical Informatics Training (CBIT) initiative. This course is designed as the third course of a year-long sequence and is worth 100 units. Registration for the full year is expected.

Prerequisites: CCTS 47005 during Fall 2016 and 47006 in Winter 2017.

 

Winter 2017 Courses

CCTS 20400
Health Disparities in Breast Cancer

Instructor:  Eileen Dolan
Time: Mondays and Wednesdays, 10:30-11:50 am
Location: BSLC 202
Across the globe, breast cancer is the most common women’s cancer. In the last two decades, there have been significant advances in breast cancer detection and treatment that have resulted in improved survival rates. Yet, not all populations have benefited equally from these improvements, and there continues to be a disproportionate burden of breast cancer felt by different populations. In the U.S., for example, white women have the highest incidence of breast cancer but African-American women have the highest breast cancer mortality overall. The socioeconomic, environmental, biological, and cultural factors that collectively contribute to these disparities are being identified with a growing emphasis on health disparities research efforts.  In this 10-week discussion-based course students will meet twice weekly and cover major aspects of breast cancer disparities.

CCTS 40200
Cancer Bio -2: Molecular Mechanisms Cancer Biology

Instructor: Donald Vander Griend
Time: Mondays, Wednesdays, and Fridays 10:30 am-12:20 pm
Location: BSLC 240
This course provides students with an in-depth understanding of how key cellular processes are deregulated in cancer and the molecular mechanisms underpinning these defects. The course covers cell cycle checkpoint control, cell death, tumor suppressor and oncogene function, DNA repair mechanisms, epigenetics of cancer, nuclear hormone receptor activity in cancer, tumor metabolism, hypoxia responses, angiogenesis and metastasis. In addition to material covered in formal lectures, discussion sessions cover tumor stem cells, "oncogene addiction," inflammatory responses, cancer therapeutics, mouse models of human cancer and other topical subjects relevant to understanding tumor initiation and progression, as well as how current research may facilitate cancer treatment.

CCTS 43000
Introduction to Global Health

Instructor: Christine Babcock, Nana Fenny
Time: Tuesdays and Thursdays, 12:00-1:20 pm
Location: BSLC 324
This course provides an overview of global health from the historical perspective to the current state of global health. The course features weekly guest lecturers with a broad range of expertise in the field: topics include the social and economic determinants of health, the economics of global health, global burden of disease, and globalization of health risks, as well as the importance of ethics, human rights, and diplomacy in promoting a healthier world. The course is designed for graduate-level students and senior undergraduates with an interest in global health work in resource-limited settings.

CCTS 47002
Advanced Community Based Participatory Research (CBPR) Training Program 2

Instructor: Deborah Burnet and Doriane Miller
Time: TBA
Location: TBA
The goal of health-related research is to improve the lives of people in the community studied. In traditional research, the community is not actively involved in designing the projects. Community-based participatory research is a partnership approach to research that equitably involves community members, organizational representatives, and academic researchers in all aspects of the research process. The Advanced CBPR Training Program is designed to help meet the growing need and demand for educational resources that help build the knowledge and skills needed to develop and sustain effective CBPR partnerships. The Program consists of six sessions that are offered on various Fridays throughout the year.

CCTS 47006
Methods in Health and Biomedical Informatics II

Instructors: David McClintock and Samuel Volchenboum
Time: Thursdays, 1:30-3:30 pm, From January 12 until March 9
Location: Varies between Northwestern downtown campus, UIC, and UC
Most Health and Biomedical Informatics (HBMI) Graduate Programs around the country have independently come to the conclusion that the computational methods that informatics graduate students need to be familiar with is too broad and numerous to be addressed by a series of independent courses. Therefore, most programs have created a set of integrated courses that expose the students to a wide variety of informatics methods in short modules. Typically, these required methods series are organized as a series of required courses taken during the first year of graduate study. This course is the result of discussions by Health and Biomedical Informatics researchers and educators from the Chicago Biomedical Informatics Training (CBIT) initiative. This course is designed as the second course of a year-long sequence and is worth 100 units. Registration for the full year is expected.

Fall 2016 Courses

CCTS 40004
Advanced Clinical Pharmacology I: Pharmacokinetics, Pharmacodynamics and Drug Development

Instructor:  Manish Sharma
Time: Thursdays, 1:30-2:50 pm
Location: BH-M214
This course provides an interactive introduction to fundamental principles of the practice of clinical pharmacology relevant to drug development and personalized therapeutics. Topics include: pharmacokinetics, drug metabolism, protein binding, absorption and renal and hepatic elimination, pharmacodynamics, introduction to modeling methods, evaluation of adverse events, and pre-clinical and clinical elements of drug development.

PQ: MEDC 30777, equiv Intro to Pharm., approval.

CCTS 46001
Fundamentals of Quality Improvement and Patient Safety
Instructor: Andrew Davis, Laura Botwinick
Time: Tuesdays, 5:00-6:30 pm, October 11 - November 22
Location: BH-H300
Quality Improvement & Patient Safety The course was designed for medical faculty, fellows, nursing and pharmacy professionals, clinical administrators, and staff at University of Chicago Medicine with the support of the Center for Clinical and Translational Science (CCTS) and the Center for Quality. The course provides an overview of concepts and methodologies for improving the quality and safety of care.  Participants will design quality improvement projects using skills learned in class.  In addition, UCMC leaders and experts from the Center for Quality and Operational Excellence will speak on key topics throughout the course. 

Key objectives for the course include:

  • To become familiar with tools of improving quality of care and service delivery
  • To design an actual quality improvement project using skills learned in the class
  • To understand the factors impacting the delivery of safe and high quality care in health care organizations, such as teamwork, good communication, and organization culture
  • To  understand “Systems Thinking” and other key concepts like Human Factors and Reliability
  • To understand the key role of QI in today’s health care environment as a mechanism for improving organizational effectiveness and the patient experience

This course will run from 10/11/2016-11/22/2016 and is comprised of seven classes total. Faculty, staff, and students/trainees at the University of Chicago Medical Center are welcome to audit the course at no charge and should contact Kelsey Bogue at kbogue@bsd.uchicago.edu to register. To earn 025 credits, please enroll in the course at classes.uchicago.edu.

CCTS 47001
Advanced Community Based Participatory Research (CBPR) Training Program 1

Instructor: Deborah Burnet, Doriane Miller
Time: Various
Location: Various
The goal of health-related research is to improve the lives of people in the community studied. In traditional research, the community is not actively involved in designing the projects. Community-based participatory research is a partnership approach to research that equitably involves community members, organizational representatives, and academic researchers in all aspects of the research process. The Advanced CBPR Training Program is designed to help meet the growing need and demand for educational resources that help build the knowledge and skills needed to develop and sustain effective CBPR partnerships. The Program consists of six sessions that are offered on various Fridays throughout the year.

Registrants who wish to receive 025 units of course credit must enroll through the University Registrar's office for CCTS 47001 in the fall and CCTS 47002 in the winter. Participants must also register online here whether or not they choose to take the course for credit. 

CCTS 47005
Methods in Health and Biomedical Informatics I

Instructors: Samuel Volchenboum, David McClintock, and other Northwestern/UIC faculty
Time: Thursdays, 1:30-3:30 pm, From September 22 until December 1
Location: Varies between Northwestern downtown campus, UIC, and UC
Most Health and Biomedical Informatics (HBMI) Graduate Programs around the country have independently come to the conclusion that the computational methods that informatics graduate students need to be familiar with is too broad and numerous to be addressed by a series of independent courses. Therefore, most programs have created a set of integrated courses that expose the students to a wide variety of informatics methods in short modules. Typically, these required methods series are organized as a series of required courses taken during the first year of graduate study. This course is the result of discussions by Health and Biomedical Informatics researchers and educators from the Chicago Biomedical Informatics Training (CBIT) initiative. This course is designed as a first course of a year-long sequence and is worth 100 units. Methods in Health and Biomedical Informatics II (CCTS 47006) and III (CCTS 47007) will be offered in winter and spring quarters, respectively. Registration for the full year is expected.

PQ: Basic understanding of Python programming language; prior or simultaneous enrollment in Health & Biomedical Informatics (HBMI) intro course. Course begins 9/22/2016 and runs until 12/1/2016. An orientation session will also take place on September 8 from 1:30-5:00 pm at Northwestern's downtown campus. More information about the course schedule will be announced at a later date. Send questionsa bout enrollment to kbogue@bsd.uchicago.edu.

Summer 2016 Courses

CCTS 45000
Introduction to Biostatistics

Instructor: Sydeaka Watson
Time: Tuesday, Wednesday, Thursday, 3:00pm-4:30pm
Location: BSLC-240
This course will provide an introduction to the basic concepts of statistics as applied to the biomedical and public health sciences.  Emphasis is on the use and interpretation of statistical tools for data analysis. Topics include descriptive statistics, probability and sampling, the methods of statistical inference, and an introduction to linear and logistics regression.

In addition to the course, there is a statisitcal computing workshop on Wednesdays from 10:00-11:30 am.

CCTS 45100
Clinical Epidemiology

Instructors: Brian Chiu, Diane Lauderdale
Time: Tuesdays and Thursdays, 9:00am - 11:00am
Location: BSLC-240
Clinical epidemiology is the "application of epidemiologic principles and methods to problems encountered in clinical medicine."  This course introduces the basic principles of epidemiologic study design, analysis and interpretation, with a particular focus on clinincal applications. The course inclused lectures and discussions based on critical appraisal of significant research articles.

CCTS 45200
Fundamentals of Health Services Research: Theory, Methods and Applications

Instructor: David Meltzer and Marshall Chin
Time: Monday, Tuesday, Wednesday, Thursday, and Friday, 1:00pm - 2:30pm
Location: BH-H300
This course is designed to provide an introduction to the fundamentals of health services research. The basic concepts of health services research will be taught with emphasis on both their social scientific foundations and the methods needed for their practical application to empirically relevant research. Theoretical foundations will draw on principles from economics, sociology, psychology, and other social sciences. Methodological topics to be covered will include techniques for data collection and analysis, including outcomes measurement, survey methods, large data set research, population-based study design, community based participatory research, research based in clinincal settings, qualitative methods, cost-effectiveness analysis, and tools of economic and sociological analysis. The theoretical and empirical techniques taught will emphasize those relevant to the examination of health care costs, quality, and access. Major applications will include: measurement and improvement of health care quality, analysis of health disparities, analysis of health care technology, and analysis of health care systems and markets.